Sickle Cell Disease

News: To commemorate the World Sickle Cell Disease (SCD) Day on 19th June, the Ministry of Tribal Affairs (MOTA) flagged off mobile vans under the Unmukt project for strengthening screening and timely management of SCD in tribal districts of Jharkhand and Chhattisgarh. The United Nations General Assembly (UNGA) adopted a resolution recognising SCD as a public health problem on 22th December, 2008. The UNGA also recognised SCD as one of the first genetic diseases.

Sickle Cell Disease:

  • It is an inherited blood diseasewhich is most common among people of African, Arabian and Indian origin. It is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disease have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent shape.
  • This blocks blood flow and oxygen from reaching all parts of the body.
  • It can cause severe pain, referred to as sickle cell crises. Over time, people with sickle cell disorders can experience damage to organs including the liver, kidney, lungs, heart and spleen.Death can also result from complications of the disorder.
  • Treatments available are Medication, blood transfusions and rarely a bone-marrow transplant.
  • India alone is home to about 1,50,000 patients with SCD and about 88% of Sickle Cell Anemia (SCA) cases in Asia. The disease in India occurs predominantly in eastern Gujarat, Maharashtra, Madhya Pradesh, Chhattisgarh, western Odishaand in pockets of the Nilgiri Hills in north Tamil Nadu and Kerala.
  • The disease is prevalent among tribal communities(including children).
  • As per MOTA, SCD is affecting more women and children and nearly 20% of tribal children with SCD die before reaching the age of two, and 30% children die before reaching adulthood.